The Effect of Occlusive Dressings on Collagen Synthesis and Re-epithelialization in Superficial Wounds

The effects on superficial wounds in domestic pigs of (1) two different occlusive dressings, (2) nonocclusive wet to dry gauze dressings, and (3) air exposure were compared. Collagen synthesis and reepithelialixation were increased in the wounds treated with occlusive dressings. Re-epitheliahzation was increased beneath both the oxygen-impermeable and the oxygen-permeable dressing. When they were removed the wet to dry gauze dressing and one of the occlusive dressings often damaged the new
epidermis.

Formation of the Scab and the Rate ofEpithelization of Superficial Wounds inthe Skin of the Young Domestic Pig

探讨医用眼部保护敷贴在眼底手术中健眼的应用

探讨目宁康医用眼部保护敷贴在眼底手术中对健眼的保护。方法 将 100 例在球后神经阻滞麻醉下进行眼底手术的患者随机分为观察组和对照组，每组 50 例。观察组术中全部使用医用眼部保护敷贴，对照组嘱患者术中自然闭眼不采取任何保护措施。比较两组患者术中感受、配合程度及术后健眼是否出现结膜充血、疼痛、异物感、畏光流泪，视物模糊等不适症状。结果 两组患者术中配合程度、术中感受及术后健眼眼部情况比较具有统计学意义（P < 0.05）。结论 目宁康医用眼部保护敷贴具有很好的保湿作用和密封性，在眼底手术中使用，使患者的健眼处于理想的湿润环境中，不仅防止术后出现健眼的不适症状，而且对于患者健眼的舒适度也大大提高更好的配合医生手术，保证手术的进行。

Effect of Air Exposure and Occlusion on Experimental Human Skin Wounds

Functional Hydrogels as Wound Dressing to Enhance Wound Healing

Hydrogels, due to their excellent biochemical and mechnical property, have shown attractive advantages in the field of wound dressings. However, a comprehensive review of the functional hydrogel as a wound dressing is still lacking. This work first summarizes the skin wound healing process and relates evaluation parameters and then reviews the advanced functions of hydrogel dressings such as antimicrobial property, adhesion and hemostasis, anti-inflammatory and anti-oxidation, substance delivery, self-healing, stimulus response, conductivity, and the recently emerged wound monitoring feature, and the strategies adopted to achieve these functions are all classified and discussed. Furthermore, applications of hydrogel wound dressing for the treatment of different types of wounds such as incisional wound and the excisional wound are summarized. Chronic wounds are also mentioned, and the focus of attention on infected wounds, burn wounds, and diabetic wounds is discussed. Finally, the future directions of hydrogel wound dressings for wound healing are further proposed.

水凝胶防治化疗性静脉炎的临床研究

探索有效防治恶性肿瘤患者化疗性静脉炎的护理措施。 方法 将 150 例恶性肿瘤定期接受化疗的患者随机分为 3 组，水凝胶组、土豆片组和对照组，每组各 50 例。 分别给予水凝胶外敷、新鲜土豆片外敷及常规预防措施，比较 3 组患者静脉炎的发生率、程度和发生时间。 结果 水凝胶组静脉炎发生率为 8.0%，明显低于对照组（42.0%）和土豆片组（22.0%，P ＜0.05）；水凝胶组静脉炎发生时间（6.2 d）明显长于对照组（3.6 d，P ＜ 0.05）。 对照组和土豆片组静脉炎严重程度明显高于水凝胶组，3 组之间比较，差异有统计学意义（P ＜ 0.05）。 结论 采用水凝胶外敷能有效防治恶性肿瘤患者化疗性静脉炎的发生。

水凝胶在局限期前列腺癌放疗中的研究进展

近年来，我国前列腺癌的发病率呈逐年上升趋势。 局限期前列腺癌的手术治疗与外放 疗的效果相似。 由于直肠靠近前列腺，对前列腺癌进行放疗常导致放射性直肠炎。 国外学者尝试在 直肠与前列腺间隙注入聚乙二醇水凝胶，以隔开直肠与前列腺，进而降低直肠受量和放射性直肠炎的 发生率